C1 Esterase Inhibitor Deficiency. C1 esterase inhibitor C1-INH is a protein found in the fluid part of your blood. Introduction Acquired angioedema AAE due to deficiency of C1-inhibitor is a relatively infrequently occurring but serious disorder resulting in severe sometimes life-threatening episodes of angioedema.
Adults or elderly patients are most commonly affected. The test includes functional C1 esterase inhibitor C3 and C4 levels. C4 and C2 are complementary components.
Introduction Acquired angioedema AAE due to deficiency of C1-inhibitor is a relatively infrequently occurring but serious disorder resulting in severe sometimes life-threatening episodes of angioedema.
C1 esterase inhibitor C1-INH is a protein found in the fluid part of your blood. The complement system is a group of nearly 60 proteins in blood plasma or on the surface of some cells. Analysis of complement C1 inhibitor levels may play a role in diagnosis. The diagnosis is suspected when patients present with recurrent angioedema and low serum levels of C4 with normal levels of C3.
