Tryptase Level. The rise in tryptase levels starts to be detected in serum within minutes of anaphylaxis but the level will gradually revert to normal over the next 624 hours depending on the height of the increase and often correlates with the severity of the anaphylaxis. Click here for more.
A persistently elevated baseline level of tryptase above 20 μgl is an indication of possible. Elevated serum tryptase levels 115 ngmL were found in 9 of 15 patients with HES and both patients with systemic mastocytosis Figure 1. Given the lack of other symptoms it would be reasonable to monitor the patient clinically as well rechecking the tryptase level in the future.
Horwitz explained that plasma levels of tryptase are usually too low to measure in individuals who dont have mastocytosis or anaphylaxis.
If baseline total serum tryptase levels exceed 20 ngmL systemic mastocytosis should be suspected. Given the lack of other symptoms it would be reasonable to monitor the patient clinically as well rechecking the tryptase level in the future. The rise in tryptase levels starts to be detected in serum within minutes of anaphylaxis but the level will gradually revert to normal over the next 624 hours depending on the height of the increase and often correlates with the severity of the anaphylaxis. Elevated Tryptase level and not its dcrease is important in diagnosis of mast cell activation disorders Therefore decreased level of tryptase has no clinical importance.
